April Greiman received a BFA degree for the Kansas Art Institute and went to graduate school at the Basel School of Design in Switzerland in the early 1970s.

April was chair of the graphic design program at CalArts from 1981 to 1984. She immersed herself in new media, spending her spare time exploring digital technology, using video and analogue computers to combine different elements for new and provocative image making potential. Greiman’s California New Wave typography and mixed media design shook up the Modernist designers for a few years when she began questioning the design community's preconceptions of what constitutes design in 1986.

Greiman has always been on the cutting edge of design with her curiosity and desire to explore new media, typography, symbolism, and hybrid processes. She was the leading exponent of integrated design in the 1990's.